HSDD DEFINED
Hypoactive sexual desire disorder (HSDD) is the most prevalent form of female sexual dysfunction (FSD)1
- Spontaneous desire (including sexual thoughts, fantasies, stimulation)
- Desire to initiate or participate in sexual activity
In addition to low sexual desire, clinically significant personal distress is central to the diagnosis of HSDD. Distress is defined as feelings of frustration, grief, incompetence, loss, sadness, sorrow, or worry.3,4
*Developed and accepted for use by the International Society for the Study of Women’s Sexual Health (ISSWSH) and members of other participating societies.5



Her HSDD Story: Jen, 45
Jen discovers she may have HSDD.
FSD is an umbrella term used to describe various sexual problems1
- Hypoactive sexual desire disorder (HSDD)
- Diminished sexual arousal
- Orgasmic difficulties
- Dyspareunia
RESULTS OF A PRESIDE SURVEY OF 31,581 WOMEN ReVEALED†
Women with FSD also experience emotional and psychological distress1
In the survey, women were ~2x more likely to be bothered by low sexual desire than other sexual problems.


PRESIDE=Prevalence of Female Sexual Problems Associated with Distress and Determinants of Treatment.
†PRESIDE is a cross-sectional, large population-based survey of female adults in the United States. The purpose was to estimate the prevalence of self-reported sexual problems of desire, arousal, and orgasm, the prevalence of sexually related personal distress, and their combination, and to identify associated factors. Women in survey were stratified into 3 age groups (18-44 years [n=12,959], 45-64 years [n=11,900], and ≥65 years [n=6,338]). The numbers depicted are US population age-adjusted estimates based on women aged 18 to 44 years in the PRESIDE population (n=12,959).



HSDD is different from other female sexual dysfunctions because HSDD includes both low sexual desire and clinically significant distress as part of the diagnostic criteria.3,5
HSDD can be classified based on onset and context6


What’s causing her low sexual desire and associated distress?
References
References: 1. Shifren JL, Monz BU, Russo PA, Segreti A, Johannes CB. Sexual problems and distress in United States women: prevalence and correlates. Obstet Gynecol. 2008;112(5):970‐978. 2. McCabe MP, Sharlip ID, Atalla E, et al. Definitions of sexual dysfunctions in women and men: a consensus statement from the Fourth International Consultation on Sexual Medicine 2015. J Sex Med. 2016;13(2):135-143. 3. Parish SJ, Goldstein AT, Goldstein SW, et al. Toward a more evidence‐based nosology and nomenclature for female sexual dysfunctions—part II. J Sex Med. 2016;13(12):1888-1906. 4. DeRogatis L, Clayton A, Lewis‐D’Agostino D, Wunderlich G, Fu Y. Validation of the female sexual distress scale‐revised for assessing distress in women with hypoactive sexual desire disorder. J Sex Med. 2008;5:357-364. 5. Goldstein I, Kim NN, Clayton AH, et al. Hypoactive sexual desire disorder: International Society for the Study of Women’s Sexual Health (ISSWSH) expert consensus panel review. Mayo Clin Proc. 2017;92(1):114‐128. 6. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 1994;494.